Saint John the Baptist is a High Renaissance oil painting on walnut wood by Leonardo da Vinci. Likely to have been completed between 1513 and 1516, it is believed to be his final painting. Its original size was 69 by 57 centimetres (27 in × 22 in).

The painting is in the collection of the Louvre. In November 2022, it was loaned to Louvre Abu Dhabi for two years as part of the museum's fifth anniversary.